Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 400/80mg | ||||
360 pill | 400/80mg | €132.20 | €0.37 | |
270 pill | 400/80mg | €101.55 | €0.38 | |
180 pill | 400/80mg | €74.41 | €0.41 | |
120 pill | 400/80mg | €53.40 | €0.45 | |
90 pill | 400/80mg | €42.89 | €0.47 | |
60 pill | 400/80mg | €30.63 | €0.52 | |
30 pill | 400/80mg | €17.50 | €0.57 | |
Dosage: 800/160mg | ||||
360 pill | 800/160mg | €350.20 | €0.97 | |
180 pill | 800/160mg | €184.73 | €1.02 | |
120 pill | 800/160mg | €131.32 | €1.09 | |
90 pill | 800/160mg | €103.30 | €1.15 | |
60 pill | 800/160mg | €72.66 | €1.22 | |
30 pill | 800/160mg | €37.64 | €1.26 | |
20 pill | 800/160mg | €26.26 | €1.30 | |
10 pill | 800/160mg | €13.12 | €1.31 |

Trimethoprim Description
Overview of Trimethoprim
Trimethoprim is an antimicrobial medication widely used to treat bacterial infections. It belongs to the class of drugs known as antibiotics and is particularly effective against urinary tract infections, respiratory infections, and certain gastrointestinal infections. The medication works by inhibiting bacterial DNA synthesis, which prevents the bacteria from multiplying and helps eliminate the infection from the body. Due to its effectiveness and ease of use, Trimethoprim remains a popular choice in both hospitals and outpatient settings.
How Does Trimethoprim Work?
Trimethoprim primarily targets the bacterial enzyme dihydrofolate reductase. By inhibiting this enzyme, it disrupts the production of tetrahydrofolic acid, a vital component in bacterial DNA synthesis and replication. This action results in bacteriostatic effects, meaning it stops bacteria from multiplying, giving the immune system a better chance to clear the infection. In many cases, Trimethoprim is combined with sulfamethoxazole to enhance its efficacy, forming the well-known antibiotic co-trimoxazole. However, even as a standalone drug, Trimethoprim has proven effective in various treatment protocols.
Indications and Usage
Trimethoprim is primarily prescribed for urinary tract infections caused by susceptible bacteria. It's also used in treating respiratory tract infections such as bronchitis and sinusitis. Sometimes, it is used for skin infections or ear infections when appropriate. The medication is usually taken orally, with dosage depending on the severity of the infection and patient-specific factors like age and renal function. It is important to follow the prescribed regimen and complete the entire course of therapy to prevent the development of antibiotic resistance.
Possible Side Effects
Like all medications, Trimethoprim can cause side effects. Most common reactions include gastrointestinal disturbances such as nausea, vomiting, and abdominal pain. Some individuals may experience allergic reactions, including rash, itching, or swelling. Less frequently, patients might encounter hematological effects such as anemia, leukopenia, or thrombocytopenia, especially with prolonged use. It's vital to monitor for adverse reactions and report any unusual symptoms to a healthcare provider promptly.
Precautions and Interactions
Patients with certain medical conditions, like kidney or liver impairment, should use Trimethoprim cautiously and under medical supervision. It can also interact with other medications, such as methotrexate, digoxin, and certain diuretics, potentially increasing the risk of side effects. Due to its effect on blood cell production, pregnant women and breastfeeding mothers should consult their doctor before using this medication. Proper hydration is recommended during treatment to reduce the risk of kidney stones and other complications.
Conclusion
Trimethoprim is a proven antibiotic with a well-established safety profile when used appropriately. It offers an effective option for treating various bacterial infections, especially urinary tract infections. However, responsible use is essential to prevent resistance and minimize side effects. Consulting a healthcare professional before starting therapy ensures proper dosage and monitoring, making Trimethoprim a reliable choice in bacterial infection management.