Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 25mg | ||||
360 pill | 25mg | €116.44 | €0.32 | |
180 pill | 25mg | €67.41 | €0.38 | |
120 pill | 25mg | €49.02 | €0.41 | |
90 pill | 25mg | €41.14 | €0.46 | |
60 pill | 25mg | €27.13 | €0.46 | |
30 pill | 25mg | €14.88 | €0.48 | |
Dosage: 100mg | ||||
180 pill | 100mg | €154.08 | €0.86 | |
120 pill | 100mg | €115.56 | €0.96 | |
90 pill | 100mg | €94.55 | €1.05 | |
60 pill | 100mg | €63.90 | €1.07 | |
30 pill | 100mg | €36.76 | €1.23 |

Spironolactone Description
Introduction to Spironolactone
Spironolactone is a medication classified as a potassium-sparing diuretic and an aldosterone antagonist. It is commonly used in the treatment of conditions such as heart failure, hypertension, and certain cases of edema. Its unique mechanism of action helps the body eliminate excess fluid while conserving potassium, making it a valuable option in managing fluid retention and high blood pressure.
How Spironolactone Works
This medication works by blocking the effects of aldosterone, a hormone that causes the kidneys to retain sodium and water. By inhibiting aldosterone, spironolactone promotes the excretion of water and sodium through urine. At the same time, it decreases potassium loss, which distinguishes it from other diuretics. Its target receptors are primarily located in the distal tubules of the kidneys, and this selective action contributes to its effectiveness in various conditions involving fluid overload.
Uses and Benefits
Spironolactone is widely prescribed for heart failure patients to reduce the workload on the heart, improve symptoms, and prevent hospitalizations. It is also used to treat primary hyperaldosteronism, a condition characterized by excess production of aldosterone. Additionally, it helps manage resistant hypertension that does not respond well to standard treatment. Dermatological applications include treatment of hormonal acne and hirsutism in women due to its anti-androgenic properties.
Potential Side Effects and Risks
While spironolactone is effective, it can cause side effects. Common ones include dizziness, fatigue, gastrointestinal upset, and headache. Because it spares potassium, there is a risk of hyperkalemia—excessively high potassium levels—which can be dangerous if not monitored. Other less frequent side effects involve hormonal effects such as breast tenderness, irregular menstrual cycles, or gynecomastia in men. Patients with kidney disease or those taking other medications affecting potassium levels should use this drug cautiously under medical supervision.
Usage Guidelines and Precautions
Dosage depends on the specific condition being treated and the patient's response. It is essential to follow the prescribed dose and regularly monitor potassium and kidney function levels during therapy. Patients are advised to avoid excessive salt substitutes or foods rich in potassium. Pregnant and breastfeeding women should consult their healthcare provider before using spironolactone, as it may affect fetal development or pass into breast milk. Overall, regular medical check-ups are crucial to ensure safe and effective treatment.