Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 1% | ||||
5 tube | 1% | €44.64 | €8.93 | |
4 tube | 1% | €42.02 | €10.51 | |
3 tube | 1% | €36.76 | €12.26 | |
2 tube | 1% | €28.01 | €14.00 | |
Dosage: 5% | ||||
5 tube | 5% | €109.43 | €21.89 | |
4 tube | 5% | €94.55 | €23.64 | |
3 tube | 5% | €78.79 | €26.27 | |
2 tube | 5% | €61.28 | €30.63 |

Fluorouracil Description
Overview of Fluorouracil
Fluorouracil, often abbreviated as 5-FU, is a widely used chemotherapeutic agent that belongs to the class of drugs known as antimetabolites. It is primarily employed in the treatment of various cancers, including colorectal, breast, and skin cancers. This medication works by interfering with the DNA synthesis process in rapidly dividing cancer cells, thereby inhibiting their growth and proliferation. As a cornerstone in oncology, Fluorouracil has played an essential role in improving patient outcomes and survival rates.
How Fluorouracil Works
Fluorouracil functions as a pyrimidine analog, mimicking the natural base uracil. Once introduced into the body, it is metabolized into active compounds that inhibit thymidylate synthase, an enzyme crucial for DNA replication. This inhibition leads to a depletion of thymidine triphosphate, one of the building blocks of DNA. The disruption caused by Fluorouracil hampers the ability of cancer cells to replicate their DNA, which results in cell death. Its selective toxicity towards rapidly dividing cells makes it effective against tumors while offering some level of specificity compared to other less targeted treatments.
Administration and Usage
Fluorouracil is generally administered through intravenous injection, often as part of a combination chemotherapy regimen. The dosing regimen varies depending on the type and stage of cancer being treated, as well as patient-specific factors such as age and overall health. In some cases, topical formulations of Fluorouracil are used to treat precancerous skin lesions like actinic keratosis or superficial basal cell carcinoma. It is important for patients to follow their healthcare provider's instructions carefully to maximize effectiveness and minimize side effects. Regular monitoring through blood tests and clinical assessments is essential during therapy to track progress and detect any adverse reactions early.
Potential Side Effects and Precautions
Like many chemotherapy drugs, Fluorouracil can cause a range of side effects. Common adverse reactions include nausea, vomiting, diarrhea, mouth sores, and hair loss. Some patients may also experience hematologic effects such as leukopenia, anemia, or thrombocytopenia, which can increase the risk of infections or bleeding. Severe skin reactions and hand-foot syndrome are noted in some cases, especially when topical forms are used. It is vital for patients undergoing treatment to report any unusual symptoms to their healthcare provider promptly. Precautions should be taken to avoid infections and manage side effects effectively. Patients with pre-existing conditions, such as liver or kidney impairment, should inform their doctor, as dosage adjustments may be necessary.
Conclusion
Fluorouracil remains a key drug in cancer therapy due to its proven efficacy and broad application spectrum. Its ability to target rapidly dividing cells makes it a valuable option for treating several malignancies. However, its usage requires careful management to mitigate potential side effects. Patients should always adhere to medical guidance and participate in regular monitoring while undergoing treatment with Fluorouracil to ensure the best possible outcomes. Proper handling and administration are critical in achieving therapeutic success and maintaining overall health during cancer treatment.